In this resource article, we list many of the medications most commonly used to treat narcolepsy. Many of the medications for narcolepsy are “shared care” drugs, where the consultant/specialist and GP share the monitoring of the drug. Others are not licensed for that use but, because there is evidence that they are effective, they can nonetheless be prescribed by a specialist physician. Some of the drugs that are used are licensed for the treatment of one or more symptoms of narcolepsy. Similarly, it may take some time to work out the best dose of each drug. Following your diagnosis, it is very common to try several different drugs or combinations of drugs before settling on the optimal treatment regime. What works best for one patient does not necessarily also work best for another, and you and your doctor will need to work together to find the treatment that is most suitable for you. Some people with narcolepsy are prescribed only one medicine, but for many the best results are obtained using a combination of two or more different drugs. The treatment of idiopathic hypersomnia (IH) often involves many of the same medications. As there is no cure for narcolepsy at present, the medication that is prescribed for the treatment of narcolepsy aims to control the major symptoms of the condition, particularly excessive daytime sleepiness and cataplexy.
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